Bioengineering and integrated genomics
Africa has the most diverse genetic variation in the world combined with unique environmental factors. By harnessing this unique heritage and drawing on an advanced research network, the continent’s greatest health challenges can be addressed.
The CSIR’s research focuses on developing models of ‘disease-in-a-dish’, using advanced imaging, genome engineering and stem cell technology. By combining these molecular tools, researchers can develop clinically accurate, yet inexpensive, cellular models relevant to African health burdens.
Researchers at the CSIR focus on infectious disease susceptibility and adverse drug reactions with the ultimate goal of shortening the pipeline of developing population-specific drugs using stem cell-derived macrophages and 3D-liver models to contribute to the precision medicine-based solutions needed by the continent.
News and public engagements:
Bioengineering cells for precision medication for the South African population
CSIR bioengineers are combining stemcell technology and genome engineering to help improve the efficacy and safety of medication for the African population.