Dr Dimakatso Gumede
Gumede’s research interests are in understanding the mechanisms that drive chronic inflammation and fibrosis, including skin, lung and cardiac fibrosis, using stem cell-derived models.
Gumede is a postdoctoral researcher in bioengineering and integrated genomics research. Her research focuses on using induced pluripotent stem cells (iPSCs) to create disease models to investigate therapeutic targets for systemic inflammation and HIV-associated immune activation.
She joined the CSIR in 2018 as an intern in stem cell research and disease modelling. Her PhD research focused on understanding the functional role of a gene mutation, which causes hereditary multi-systemic fibrosis using iPSC-derived models.
Expertise: Stem cell reprogramming; inflammation and tissue remodelling; cell cycle; genetics of cardiomyopathies; understanding and manipulating biological systems (mammalian systems) and understanding molecular mechanisms of metabolic syndrome and type 2 diabetes.
- BSc Biomedical Sciences, University of KwaZulu-Natal, 2008
- Hons (Med) Cell Biology, University of Cape Town, 2008
- MSc (Med) Cell Biology, University of Cape Town, 2012
- PhD (Med), University of Cape Town, 2019
Dr Dimakatso Gumededgumede@csir.co.za