Dr Janine Scholefield

CSIR senior researcher

Dr Scholefield’s research interest lies in developing physiological and population relevant models of disease in a dish.

Full Profile

Scholefield is part of the Biomedical Translational Research Initiative at the CSIR, in association with the Division of Chemical Systems and Synthetic Biology at The institute for Infectious Diseases and Molecular Medicine at the University of Cape Town (UCT).

After completing her PhD in human genetics atUCT, she spent three years as a Nuffield Medical Fellow at the University of Oxford. Since returning to South Africa she has specialised in modelling ‘disease-in-a-dish’. Her main research interest is in developing physiologically relevant cellular models of disease using advanced technologies, including super-resolution microscopy and stem cell engineering. She is specifically interested in the control of gene expression through chromatin contacts in pluripotent stem cells and terminally differentiated macrophages, especially within the unique context of the diverse South African genetic background. In addition, Scholefield is an honorary lecturer at UCT.

Expertise: Induced pluripotent stem cell technologies; Gene engineering and expression

Academic qualifications: 
  • BSc (Honours) (Human Genetics and Cell Biology), University of Cape Town, 2000
  • MSc (Human Genetics), University of Cape Town, 2005
  • PhD (Human Genetics), University of Cape Town, 2008




Contact Person

Dr Janine Scholefield