Pathogenic control of apoptosis
Measuring cellular response to infection using novel reporter markers.
Measuring cellular response to infection using novel reporter markers
Investment for further technology development and conduct relevant trials
Monitoring the cellular response to infection using a fluorescent reporter, single molecule FISH and immunofluorescent labeling, revealed that HIV1 masks DNA damage and orchestrates a complex dysregulation of lincRNAp21. By sequestering HuR in the nucleus following proviral integration, HIV1 enables lincRNAp21 degradation.
very specific report model to measure response to infection at a cellualar level
Dr Janine Scholefield Dr Musa Mhlanga Jerolen Naidoo Dr Sam Barichievy