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Production of Heterologous Extracellular Polypeptides in Yarrowia Lipolytica

Yarrowia lipolytica yeast based system for production of recombinant proteins and peptides.

Contact Person

Funzani Libago

flibago@csir.co.za

Applications

Yarrowia lipolytica yeast based system for production of recombinant proteins and peptides.

Intellectual Property

Know-how

Technology Field

Biotechnology, pharmaceuticals

Business Opportunity

Investment for further technology development and conduct relevant trials

Technology Description

This invention relates to protein and/or polypeptide production, particularly improved production of extracellular heterologous polypeptides and proteins. In particular, the invention relates to compositions of cell populations capable of improved levels of extracellular secretion relative to control populations, kits containing such compositions, methods of producing heterologous proteins of interest and recombinant microorganisms capable of improved extracellular heterologous protein production.

Benefits & Advantages

High levels of recombinant protein and peptide production for various application

Inventors

Faranani Ramagoma Bethuel Bethuel Nthangeni Petrus Jakobus van Zyl