Biomanufacturing Industry Development Centre
The CSIR Biomanufacturing Industry Development Centre Programme
The CSIR Biomanufacturing Industry Development Centre (BIDC) is a world-class facility established to translate biomanufacturing concepts and technologies into market-ready products and services. The facility offers competency throughout the value chain, from laboratory scale validation through to technology prototyping and pilot manufacture.
The BIDC provides process and product development, process optimisation, scale-up, regulatory support, commercial manufacturing services and incubation of SMMEs to enable the development of a vibrant and sustainable bioeconomy in South Africa and throughout the African continent.
The BIDC was established to translate biotechnology-based research and development (R&D) into market-ready products and services. The project is housed at the CSIR and offers competency throughout the value chain, i.e. from laboratory scale validation through to demonstration of technology, prototyping and pilot manufacturing.
The BIDC is a hub for open innovation in biomanufacturing and has a strong focus on supporting start-up and small, medium and micro enterprises (SMMEs) with the development of new technologies and products. It provides incubated companies with access to ready-to-use biomanufacturing facilities and supporting R&D laboratories. The programme also provides access to experts in the fields related to bioprocess development, prototyping, pilot manufacturing and scale-up capabilities. The hub includes laboratories for molecular biology, applied biochemistry, biocatalysis and fermentation, as well as laboratory and pilot-scale process development. These facilities are complemented by high-end analytical infrastructure at the CSIR.
The BIDC has since been funded by National Treasury’s Jobs Fund Programme and the Department of Science and Technology’s Industry Innovation Support Fund. The BIDC programme and its facilities are accessible to the National System of Innovation and can provide contract R&D, process development, process optimisation, scale-up, regulatory support, commercial manufacturing services and incubation of SMMEs to enable the development of a vibrant and sustainable bioeconomy in South Africa and throughout the continent.
The BIDC Advisory Panel and Steering Committee advises on which companies to support. The programme will support companies through the prototyping and scale-up phase and assist them to do market acceptance testing and to launch products on the market. The companies remain the sole owners of their innovations and retain absolute control over their future in terms of added value and partnerships.
To be the leading centre that translates biosciences discoveries into products and technologies with impact to industry and society.
Our objectives are to:
- stimulate the growth of a biomanufacturing-based economy and create sustainable jobs in a new industry value chain
- consolidate and strengthen specialist bioprocess/product development competencies including infrastructure at the CSIR and
- use the strengthened bioprocessing competency to provide affordable and readily accessible support to SMMEs in the biomanufacturing sector in order penetrate and grow their target markets.
- Technology demonstration and validation at lab scale;
- Product development and prototyping;
- Scale-up of technologies to pilot scale;
- Biochemical analysis; and
- Contract manufacturing.
Labs, facilities and skills:
- Research & Development Labs include: Molecular Biology, Protein Purification, and 1 litre fermentation laboratory
- Chemical laboratories and analytical infrastructure
- Natural products pilot facility up to 400 litre
- 20 litre bioprocessing facility
- 200 litre and 1 000 litre bioreactors housed in the bioprocessing pilot plant
- Downstream processing (DSP) facility: product isolation, purification and polishing
- Product formulation and packaging
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