Multiomics
Multiomics is a holistic approach to clinical research that integrates genomics, proteomics, transcriptomics, and other ‘omics’ layers to create a more complete understanding of biological processes, health and disease states. Through integrated multiome analyses and AI-guided discovery, we can address questions too complex for any single ‘ome’ to explain on its own – unlocking novel insights into disease biology and driving health innovation.
Contact information:
Highlights
African Clinical Multiome Atlas Platform (Clin-MAP)
The CSIR is leveraging the unique convergence of clinical access, multiome expertise and digital infrastructure across multinational clinical-research collaborations to establish an African-relevant multiome data repository. The selection of clinical cohorts is focused on future high-impact African health priority areas and previously underserved population groups. The African Clinical Multiome Atlas Platform (Clin-MAP) will serve as a catalyst for sustainable African-led health innovation by aligning multisectoral interests towards real-world impact.
Clin-MAP Overview
The African Clinical Multiome Atlas Platform (Clin-MAP) will serve as a catalyst for sustainable African-led health innovation by aligning multisectoral interests towards real-world impact.
Clin-MAP partner network
The CSIR is leveraging the unique convergence of clinical access, multiome expertise and digital infrastructure across multinational clinical-research collaborations to establish an African-relevant multiome data repository.
Capabilities
Proteomics
The CSIR Proteomics Core Facility is the national centre for advanced mass spectrometry-based proteomics, providing not just state-of-the-art instrumentation but also unparalleled expertise from experimental design to data interpretation, enabling impactful biological discoveries and translating research into technological solutions for national benefit.
Transcriptomics and genomics
Expertise in single cell, bulk RNA-seq and NGS-based genomic profiling methods across diverse technology platforms and sample types (clinical and cell-based) - from bench to analysis.
Microbiomics
From NGS-based microbiome profiling (16S and shotgun metagenomics) of clinical samples to functional investigations of microbiome host-interactions through cell-based models and high content screening.
Organoid technologies
Expertise in the derivation of organoid models and tissue processing for downstream multiome profiling assays and high content screening.
Our facilities
Our work is supported by technical expertise and collaborative frameworks to accelerate translational research in precision medicine for African populations. This includes integrated capabilities across cutting edge fields like organoid technologies, proteomics, single cell transcriptomics, epigenomics, and microbiomics.
